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Science quotes on curiosity and not fooling yourself

Feynman's rule is the spine of this one: the easiest person to fool is you. Add Einstein on imagination, Huberman on mechanism, and a working definition of honest thinking.

24 here · 261 in the app · 29 authors

  1. It's a kind of scientific integrity, a principle of scientific thought that corresponds to a kind of utter honesty—a kind of leaning over backwards.
  2. A wealth of data indicate that deliberate neuroplasticity (your brain’s ability change in response to specific intended experiences): 1) requires focus during learning 2) actual rewiring occurs in sleep 3) is accelerated by increasing adrenaline immediately POST learning
  3. In summary, the idea is to try to give all of the information to help others to judge the value of your contribution; not just the information that leads to judgment in one particular direction or another.
  4. Most are adept at cycles of focus followed by rest in the form of weekends, vacation, etc. Learning how to engage work-rest cycles on shorter time scales (daily hourly, etc) creates an outsized effect on productivity & health.
  5. AI is probabilistic while crypto is deterministic.
    Balaji Srinivasan"AI is polytheistic, not monotheistic", balajis.com · 2025
  6. The shorter your sleep, the shorter your life span.
    Matthew WalkerWhy We Sleep, Introduction · 2017
  7. AI is amplified intelligence, not artificial intelligence.
    Balaji Srinivasan"AI is polytheistic, not monotheistic", balajis.com · 2025
  8. All I ask is that we are honest about what the science says.
    Layne NortonThe Game Changers Review - A Scientific Analysis · 2019
  9. If you're picked on and you're stressed, you're going to age faster.
    David SinclairThe Joe Rogan Experience #2537 · 2026
  10. The more intense the stimulus, the greater the adaptation to a degree.
    Rhonda Patrick"The Best Type of Exercise for Longevity", FoundMyFitness #108 · 2025
  11. The mitochondria are actually the most important in any part of your body.
    David SinclairThe Joe Rogan Experience #2537 · 2026
  12. The sheer stress causes your endothelial cells lining your arteries to adapt.
    Rhonda Patrick"The Best Type of Exercise for Longevity", FoundMyFitness #108 · 2025
  13. The elastic band of sleep deprivation can stretch only so far before it snaps.
    Matthew WalkerWhy We Sleep, Introduction · 2017
  14. All calories are equal, the same way each mile per hour on a gauge is the same.
    Layne NortonIt's Not Calories... It's Hormones: A Response to Dr. Jason Fung · 2021
  15. If you insist on using the technology without understanding how it works you are likely to fail.
    Andrej Karpathy"A Recipe for Training Neural Networks", karpathy.github.io · 2019
  16. A "fast and furious" approach to training neural networks does not work and only leads to suffering.
    Andrej Karpathy"A Recipe for Training Neural Networks", karpathy.github.io · 2019
  17. The Analytical Engine weaves algebraic patterns, just as the Jacquard loom weaves flowers and leaves.
    Ada LovelaceNotes on the Analytical Engine · 1843
  18. The way I think about it is longevity means how do we live longer? I think that means years longer, a decade longer.
    Peter Attia"Longevity 101", The Peter Attia Drive #311 · 2024
  19. As one of my medical school professors liked to point out, the most common "presentation" of the disease is a sudden, fatal heart attack.
    Peter Attia"Longevity 101", topic guide, peterattiamd.com · 2024
  20. That brain of mine is something more than merely mortal, as time will show.
    Ada Lovelace
  21. If a man keeps cherishing his old knowledge, so as continually to be acquiring new, he may be a teacher of others.
    ConfuciusThe Analects of Confucius, Book II, Chapter XI
  22. Very often specific knowledge is at the edge of knowledge.
    Naval RavikantNaval Podcast: Arm Yourself With Specific Knowledge · 2019
  23. Error is just as important a condition of mental progress as truth.
    Carl JungThe Theory of Psychoanalysis, Ch. IX: The Therapeutical Principles of Psychoanalysis · 1915
  24. On an evolutionary basis, if you go back thousands of years, status is a much better predictor of survival than wealth is.
    Naval RavikantNaval Podcast: Seek Wealth, Not Money or Status · 2019

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